Catalytic hydrogenation is one of the most important transformations in the chemical industry today. However, there are stringent safety requirements especially with regard to high pressure, high temperature reactions. ThalesNano's technology can be operated in a standard laboratory and dangerous hydrogenations can be performed safely. The method of flowing a stream of compound through a packed catalyst bed increases the interaction between the three phases, increasing reaction rates by orders of magnitude and making it more effective and economical.

ThalesNano offers services to perform heterogeneous hydrogenation on a wide range of chemical groups. The following is a selected list of transformations we carried out successfully for our customers.

• Enantioselective hydrogenation
• Chemoselective hydrogenation
• Deprotection of N- and O-benzyl and Cbz protecting groups
• Double bond saturation
• Nitro reduction
• Heterocycle saturation
• Nitrile and oxime reduction

ThalesNano Custom-tailored Synthesis

We perform all catalytic hydrogenations using our own technology platform, the H-Cube®. The first bench-top instrument for catalytic hydrogenation, the H-Cube®, offers markedly increased safety, efficiency and speed when compared to other hydrogenation reactors. Our custom tailored synthesis service enables customers to realize all the benefits of H-Cube® through collaborative projects with the ThalesNano team.

ThalesNano's custom synthesis services are available to customers on a fee for service basis. Our clients can specify the structures they want to receive. Customers receive regular project reports, and any intermediate compounds are made available to the customer.

For more information, please contact us at info@thalesnano.com [1]