Synthesis of a novel C2/C2’-aryl-substituated pyrrolo[2,1-c][1,4]benzodiazepine dimer produg with improved water solubility and reduced DNA reaction rate

Howard, P. W., Chen, Z., Gregson, S. J., Masterson, L. A., Tiberghien, A. C., Cooper, N., Fang, M., Coffils, M. J., Klee, S., Hartley, J. A., Thurston, D.E., Synthesis of a novel C2/C2’-aryl-substituated pyrrolo[2,1-c][1,4]benzodiazepine dimer produg with improved water solubility and reduced DNA reaction rate, Bioorg. Med. Chem. Lett., 2009, 19(22), 6463-6466
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